Article
Genetic structure of the LXS panel of recombinant inbred mouse strains: a powerful resource for complex trait analysis.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Aug 2004
Williams Robert W, Bennett Beth, Lu Lu, Gu Jing, DeFries John C, Carosone-Link Phyllis J, Rikke Brad A, Belknap John K, Johnson Thomas E
Abstract excerpt
The set of LXS recombinant inbred (RI) strains is a new and exceptionally large mapping panel that is suitable for the analysis of complex traits with comparatively high power. This panel consists of 77 strains-more than twice the size of other RI sets--and will typically provide sufficient statistical power (beta = 0.8) to map quantitative trait loci (QTLs) that account for approximately 25% of genetic variance...
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