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Article

Development of congenic rat strains for alcohol consumption derived from the alcohol-preferring and nonpreferring rats.

Behavior genetics - 1 Mar 2006

Carr Lucinda G, Habegger Kirk, Spence John P, Liu Lixiang, Lumeng Lawrence, Foroud Tatiana

Abstract excerpt

A genome scan of the F2 generation from an inbred alcohol-preferring (iP) and inbred alcohol-nonpreferring (iNP) rat cross identified a significant quantitative trait locus (QTL) on chromosome 4 with a lod score of 9.2. To confirm this QTL and to create animals for fine mapping of the QTL region, chromosome 4 reciprocal congenic strains were developed by transferring the chromosome 4 QTL interval into the...

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PMID: 16470346
DOI: 10.1007/s10519-005-9021-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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