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Article

Alterations of CDKN2 (MTS1/p16INK4A) gene in paraffin-embedded tumor tissues of human stomach, lung, cervix and liver cancers.

Experimental & molecular medicine - 30 Jun 1998

Kim J R, Kim S Y, Kim M J, Kim J H

Abstract excerpt

The CDKN2 (MTS1/p16INK4A) gene, encoding cyclin dependent kinase inhibitor, was found to be homozygously deleted at a high frequency in cell lines from many different types of cancer and some primary cancers. To determine the frequency of CDKN2 mutations in most common human cancers in Korea, PCR and PCR-SSCP analyses for the exon 2 of CDKN2 were performed on each set of 20 formalin-fixed and paraffin-embedded...

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Source

Identifiers

PMID: 9873831
DOI: 10.1038/emm.1998.16

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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Alterations of CDKN2 (MTS1/p16INK4A) gene in paraffin-embedded tumor tissues of human stomach, lung, cervix and liver cancers.PMID 9873831Read ↗

[p16INK4/CDKN2 gene deletions and mutations in non-small cell lung cancers].Semantic proximity Read ↗

Coincidental alterations of p16INK4A/CDKN2 and other genes in human lung cancer cell lines.Semantic proximity Read ↗

Higher frequency of alterations in the p16/CDKN2 gene in squamous cell carcinoma cell lines than in primary tumors of the head and neck.Semantic proximity Read ↗

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Genetic status and expression of the cyclin-dependent kinase inhibitors in human gastric carcinoma cell lines.Semantic proximity Read ↗

Genomic DNA and messenger RNA expression alterations of the CDKN2B and CDKN2 genes in esophageal squamous carcinoma cell lines.Semantic proximity Read ↗

Analysis of exon 2 of MTS1 in HPV-positive and HPV-negative tumors of the head and neck region.Semantic proximity Read ↗

Somatic mutations of the MTS (multiple tumor suppressor) 1/CDK4l (cyclin-dependent kinase-4 inhibitor) gene in human primary non-small cell lung carcinomas.Semantic proximity Read ↗

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Intragenic mutations of CDKN2B and CDKN2A in primary human esophageal cancersSemantic proximity Read ↗

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