Article
Alterations of CDKN2 (MTS1/p16INK4A) gene in paraffin-embedded tumor tissues of human stomach, lung, cervix and liver cancers.
Experimental & molecular medicine - 30 Jun 1998
Kim J R, Kim S Y, Kim M J, Kim J H
Abstract excerpt
The CDKN2 (MTS1/p16INK4A) gene, encoding cyclin dependent kinase inhibitor, was found to be homozygously deleted at a high frequency in cell lines from many different types of cancer and some primary cancers. To determine the frequency of CDKN2 mutations in most common human cancers in Korea, PCR...
Topics
- Adenocarcinoma
- Carcinoma, Hepatocellular
- Cyclin-Dependent Kinase Inhibitor p16
- Female
- Formaldehyde
- Humans
- Liver Neoplasms
- Lung Neoplasms
- Mutation
- Paraffin Embedding
- Sequence Deletion
- Stomach Neoplasms
- Tissue Embedding
- Uterine Cervical Neoplasms
