Article
Coincidental alterations of p16INK4A/CDKN2 and other genes in human lung cancer cell lines.
Anticancer research - 1 Jan 2000
Fujishita T, Mizushima Y, Kashii T, Kobayashi M
Abstract excerpt
Cyclin-dependent kinase (CDK) inhibitor genes have recently been proposed as new tumor suppressor genes. To define the possible participation of CDK inhibitor genes in lung carcinogenesis, we investigated the alterations of p15INK4B, p16INK4A, p21Waf1, and p27Kip1 genes in 34 human lung cancer ce...
Topics
- Base Sequence
- Carrier Proteins
- Cell Cycle Proteins
- Cell Line
- Colonic Neoplasms
- Cyclin-Dependent Kinase Inhibitor p15
- Cyclin-Dependent Kinase Inhibitor p16
- Cyclin-Dependent Kinase Inhibitor p21
- Cyclin-Dependent Kinase Inhibitor p27
- Cyclin-Dependent Kinases
- Cyclins
- DNA Primers
- DNA, Neoplasm
- Exons
- Frameshift Mutation
- Genes, Retinoblastoma
- Genes, myc
- Genes, ras