Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic status and expression of the cyclin-dependent kinase inhibitors in human gastric carcinoma cell lines.

Japanese journal of cancer research : Gann - 1 Aug 1996

Akama Y, Yasui W, Kuniyasu H, Yokozaki H, Akagi M, Tahara H, Ishikawa T, Tahara E

Abstract excerpt

Deregulation of cyclin, cyclin-dependent kinases (CDKs) and their inhibitors could have a pivotal role in the development of diverse human cancers. We examined the genetic status and the expression of CDK inhibitors (p21, p27, p16 and p15), CDK2 and cyclins (A, D1 and E) in eight gastric carcinoma cell lines, in comparison with the status of p53 gene alterations. All the cell lines (except MKN-28) that contained...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma
Share to Carrier Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Cycle Proteins

Share to Cyclins

Share to DNA Probes

Share to Enzyme Inhibitors

Share to Gene Expression

Share to Genes, p53

Source

Open in PubMed Open full text

Identifiers

PMID: 8797888
DOI: 10.1111/j.1349-7006.1996.tb02106.x
PMCID: PMC5921170

Genes

CDK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic status and expression of the cyclin-dependent kinase inhibitors in human gastric carcinoma cell lines.PMID 8797888Read ↗

Cell cycle-related gene abnormalities and product expression in esophageal carcinoma.Semantic proximity Read ↗

Analysis of cell cycle-related proteins in gastric intramucosal differentiated-type cancers based on mucin phenotypes: a novel hypothesis of early gastric carcinogenesis based on mucin phenotype.Semantic proximity Read ↗

Abnormal Expression of p16<sup>INK4a</sup>, Cyclin D1, Cyclin‐Dependent Kinase 4 and Retinoblastoma Protein in Gastric CarcinomasSemantic proximity Read ↗

Expression and mutation analyses of MKK4, a candidate tumour suppressor gene encoded by chromosome 17p, in human gastric adenocarcinoma.Semantic proximity Read ↗

Expressions of Cell Cycle Regulators in Human Colorectal Cancer Cell LinesSemantic proximity Read ↗

p21 expression and mutation in gastric carcinoma: analysis by immunohistochemistry and PCR-SSCP.Semantic proximity Read ↗

Alterations of CDKN2 (MTS1/p16INK4A) gene in paraffin-embedded tumor tissues of human stomach, lung, cervix and liver cancers.Semantic proximity Read ↗

Genetic and epigenetic alterations of the cyclin-dependent kinase inhibitors p15INK4b and p16INK4a in human thyroid carcinoma cell lines and primary thyroid carcinomasSemantic proximity Read ↗

Mutated p53 protein expression and proliferative activity in advanced gastric cancer.Semantic proximity Read ↗

Overexpression of mutant p53 and c-erbB-2 proteins and mutations of the p15 and p16 genes in human gastric carcinoma: with respect to histological subtypes and stages.Semantic proximity Read ↗

p53 gene mutations in gastric cancer metastases and in gastric cancer cell lines derived from metastases.Semantic proximity Read ↗

Frequent Amplification of the Cyclin E Gene in Human Gastric CarcinomasSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.