[Multiple tumor suppressor 1/p16 gene alterations in human esophageal squamous-cell carcinoma: clinical significance and regional difference].

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Article

[Multiple tumor suppressor 1/p16 gene alterations in human esophageal squamous-cell carcinoma: clinical significance and regional difference].

Zhonghua zhong liu za zhi [Chinese journal of oncology] - 1 Sept 1999

Lü G, Chen X, Cao W

Abstract excerpt

OBJECTIVE: To further understand multiple tumor suppressor 1/p16 (mts1/p16) gene alterations in squamous-cell esophageal carcinoma (EC) in relation to its biologic behavior and regional difference. METHODS: Samples of human EC from 92 patients residing in Zhejiang province and in Linxian, Henan province were analyzed for the expression, mutation and deletion of the multiple tumor suppressor gene (mts1/p16) by...

Topics

Carcinoma, Squamous Cell
Esophageal Neoplasms
Gene Deletion
Genes, p16
Humans
Mutation

Source

Open in PubMed

Identifiers

PMID: 11776574

Provenance

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