[p16INK4/CDKN2 gene deletions and mutations in non-small cell lung cancers].

Article

[p16INK4/CDKN2 gene deletions and mutations in non-small cell lung cancers].

Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 10 Feb 1998

Wang G, Du C, Lin Q

Abstract excerpt

OBJECTIVE: To investigate the genomic status of cyclindependent kinase-4 inhibitor, p16 INK4/CDKN2 gene in primary non-small cell lung cancers. METHODS: p16 gene was analysed by duplex PCR, PCR-SSCP, and sequencing in 31 primary non-small cell lung cancer (NSCLC) tissues. RESULTS: Gene deletions...

Topics

Adult
Carcinoma, Non-Small-Cell Lung
Female
Gene Deletion
Genes, p16
Humans
Lung Neoplasms
Male
Middle Aged
Mutation

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