In vivo somatic mutations in Werner's syndrome.

doi:10.1007/s004390050841

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Article

In vivo somatic mutations in Werner's syndrome.

Human genetics - 1 Oct 1998

Kyoizumi S, Kusunoki Y, Seyama T, Hatamochi A, Goto M

Abstract excerpt

The frequencies of mutant erythrocytes with loss of heterozygosity at the glycophorin A (GPA) locus and mutant CD4+ T cells lacking surface expression of the T-cell receptor alphabeta (TCR)/CD3 complex were measured by flow cytometry for Japanese Werner's syndrome (WRN) patients. The hemizygous a...

Topics

Adult
Age Factors
Bloom Syndrome
Erythrocytes
Female
Flow Cytometry
Gene Frequency
Glycophorins
Humans
Loss of Heterozygosity
Male
Middle Aged
Mutation
Receptor-CD3 Complex, Antigen, T-Cell
Werner Syndrome

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