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Article

In vivo somatic mutations in Werner's syndrome.

Human genetics - 1 Oct 1998

Kyoizumi S, Kusunoki Y, Seyama T, Hatamochi A, Goto M

Abstract excerpt

The frequencies of mutant erythrocytes with loss of heterozygosity at the glycophorin A (GPA) locus and mutant CD4+ T cells lacking surface expression of the T-cell receptor alphabeta (TCR)/CD3 complex were measured by flow cytometry for Japanese Werner's syndrome (WRN) patients. The hemizygous and homozygous GPA mutant frequencies (GPA Mfs) and the TCR/CD3-defective mutant frequency (TCR Mf) in WRN patients were...

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Source

Identifiers

PMID: 9856481
DOI: 10.1007/s004390050841

Genes

WRN
BLM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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