Article
Flow cytometric measurements of somatic cell mutations in Thorotrast patients.
Japanese journal of cancer research : Gann - 1 Dec 1991
Umeki S, Kyoizumi S, Kusunoki Y, Nakamura N, Sasaki M, Mori T, Ishikawa Y, Cologne J B, Akiyama M
Abstract excerpt
Exposure to ionizing radiation has long been well-recognized as a risk factor for cancer development. Since ionizing radiation can induce mutations, an accurate way of measuring somatic mutation frequencies could be a useful tool for evaluating cancer risks. In the present study, we have examined in vivo somatic mutation frequencies at the erythrocyte glycophorin A (GPA) and T-cell receptor (TCR) loci in 18...
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