Article
The GPA in vivo somatic mutation assay.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2005
Grant Stephen G
Abstract excerpt
The glycophorin A (GPA) assay concurrently detects and quantifies two types of erythrocytes with variant phenotypes at the autosomal locus responsible for the polymorphic MN blood group. It uses a pair of allele-specific monoclonal antibodies and flow cytometry to analyze a standard population of 5 million cells efficiently. The two phenotypes detected are simple allele loss and allele loss followed by...
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