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Article

Mutation frequency in human blood cells increases with age.

Mutation research - 1 Oct 1995

Akiyama M, Kyoizumi S, Hirai Y, Kusunoki Y, Iwamoto K S, Nakamura N

Abstract excerpt

Using either the colony formation assay or flow cytometry, it is feasible to measure the frequency of rare mutant lymphocytes or erythrocytes in human peripheral blood. Accordingly, we have investigated the mutant cell frequencies of the hypoxanthine-guanine phosphoribosyltransferase and T-cell receptor genes in T lymphocytes and of the glycophorin A gene in erythrocytes of several hundred persons aged 0-96...

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Identifiers

PMID: 7565869
DOI: 10.1016/0921-8734(95)00019-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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