Article
P53 mutation in advanced stage of primary myelodysplastic syndrome.
Anticancer research - 1 Jan 2000
Tang J L, Tien H F, Lin M T, Chen P J, Chen Y C
Abstract excerpt
Polymerase chain reaction and single strand conformation polymorphism (PCR-SSCP) analysis of the p53 tumor suppressor gene (from exon 2 to 9) was performed on samples from 47 adult patients with primary myelodysplastic syndrome (MDS). Point mutation was found in 5 (11%) patients: exon 7 in 3, exo...
Topics
- Adult
- Aged
- Aged, 80 and over
- Disease Progression
- Exons
- Female
- Genetic Markers
- Humans
- Male
- Middle Aged
- Mutation
- Myelodysplastic Syndromes
- Neoplasm Staging
