Article
Mutations of the p53 tumour suppressor gene in haematologic neoplasms.
British journal of haematology - 1 Jun 1992
Mori N, Wada M, Yokota J, Terada M, Okada M, Teramura M, Masuda M, Hoshino S, Motoji T, Oshimi K
Abstract excerpt
Mutations of the p53 tumour suppressor gene have frequently been observed in several types of solid tumours and are believed to be implicated in the development of these tumours. To determine the relevance of p53 mutations in haematologic neoplasms, we performed polymerase chain reaction-single s...
Topics
- Amino Acid Sequence
- Base Sequence
- Codon
- Exons
- Genes, Tumor Suppressor
- Humans
- Leukemia
- Lymphoma
- Molecular Sequence Data
- Mutation
- Myelodysplastic Syndromes
- Polymerase Chain Reaction
- Polymorphism, Genetic
- Tumor Suppressor Protein p53