Article
TP53 mutations in myelodysplastic syndrome.
Leukemia & lymphoma - 1 Nov 1996
Misawa S, Horiike S
Abstract excerpt
Mutations of the TP53 tumor suppressor gene, contributing to the development and progression of a wide variety of human malignancies, are found in some of the patients with myelodysplastic syndromes (MDS). Previous reports revealed that TP53 mutations were found in 0-25% of patients with MDS and are closely associated with a complex abnormal karyotype including such chromosomal losses as -5/5q-, -7/7q- and/or...
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