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Article

P53 gene mutations in acute myelogenous leukaemia.

British journal of haematology - 1 Aug 1992

Hu G, Zhang W, Deisseroth A B

Abstract excerpt

A polymerase chain reaction-single strand conformation polymorphism (PCR-SSCP) assay was used to identify the exons which contained point mutations in the conserved regions (exons 4-8) of the p53 gene in 49 acute myelogenous leukaemia (AML) patients. SSCP analysis in our study was consistent with...

Topics

Base Sequence
Codon
Exons
Gene Expression Regulation, Leukemic
Genes, p53
Humans
Leukemia, Myeloid, Acute
Mutation
Polymerase Chain Reaction
Protein Conformation

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 1390233
DOI: 10.1111/j.1365-2141.1992.tb02979.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1390233-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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