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Article

Mutations in the p53 gene in myelodysplastic syndromes.

Oncogene - 1 Dec 1991

Jonveaux P, Fenaux P, Quiquandon I, Pignon J M, Laï J L, Loucheux-Lefebvre M H, Goossens M, Bauters F, Berger R

Abstract excerpt

We have examined p53 alleles in 151 DNAs from patients with myelodysplastic syndrome using single-strand conformation polymorphism analysis of polymerase chain reaction products. We focused our study on the four highly conserved regions of the p53 gene and detected five patients with aberrantly migrating fragments. We confirmed the putative mutation in each case by direct sequencing analysis. Of these five...

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PMID: 1766671

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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