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Article

Mutations in the p53 gene in myelodysplastic syndromes.

Oncogene - 1 Dec 1991

Jonveaux P, Fenaux P, Quiquandon I, Pignon J M, Laï J L, Loucheux-Lefebvre M H, Goossens M, Bauters F, Berger R

Abstract excerpt

We have examined p53 alleles in 151 DNAs from patients with myelodysplastic syndrome using single-strand conformation polymorphism analysis of polymerase chain reaction products. We focused our study on the four highly conserved regions of the p53 gene and detected five patients with aberrantly m...

Topics

Alleles
Base Sequence
Bone Marrow
Chromosome Aberrations
Chromosome Disorders
Chromosomes, Human, Pair 17
Codon
DNA
Exons
Genes, p53
Genetic Variation
Humans
Introns

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Karyotyping

Molecular Sequence Data

Mutation

Myelodysplastic Syndromes

Oligodeoxyribonucleotides

Source

Identifiers

PMID: 1766671

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1766671-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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