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Article

Detection of p53 mutations using nonradioactive SSCP analysis: p53 is not frequently mutated in myelodysplastic syndromes (MDS).

Annals of hematology - 1 Nov 1993

Neubauer A, Brendel C, Vogel D, Schmidt C A, Heide I, Huhn D

Abstract excerpt

p53 is one of the most frequently mutated genes in human cancers. Since p53 has been implicated in lymphatic and some myeloid leukemias, such as the blastic phase of chronic myelogenous leukemia, we sought to address the role of p53 gene mutations within exons 4-9 in myelodysplastic syndromes (MD...

Topics

Alleles
DNA, Single-Stranded
Genes, p53
Humans
Mutation
Myelodysplastic Syndromes
Nucleic Acid Conformation
Point Mutation
Polymorphism, Genetic
Silver Staining
Tumor Cells, Cultured

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 8241345
DOI: 10.1007/BF01715051

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8241345-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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