Article
PMA-induced phenotypic changes in K562 cells: MAPK-dependent and -independent events.
Leukemia - 1 Dec 1998
Shelly C, Petruzzelli L, Herrera R
Abstract excerpt
Erythroid and megakaryocyte lineages are closely linked and may share a common bipotent progenitor. However, the mechanisms associated with cell lineage commitment are not fully understood. The K562 erythroleukemia cell line serves as a model to study the biochemical changes associated with erythroid and megakaryocyte (E/M) differentiation. We have previously established that PMA-induced megakaryocyte...
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