Article
Protein kinase C-zeta overexpression induces erythroid phenotype in the monocytic leukaemia cell line U937.
British journal of haematology - 1 Aug 2002
Mansat-De Mas Véronique, de Thonel Aurélie, Gaulin Vanessa, Demur Cécile, Laurent Guy, Quillet-Mary Anne
Abstract excerpt
Previous studies have established that protein kinase C-zeta (PKC-zeta) is critical for neuronal cell differentiation. However, the role of PKC-zeta in haematopoietic cell differentiation is less clear. In this study, we have investigated the influence of PKC-zeta overexpression on the phenotype of the human monocytic U937 leukaemic cells. In two PKC-zeta-overexpressing clones (U937 zetaJ and U937 zetaB),...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
