Article
A lineage-specific protein kinase crucial for myeloid maturation.
Proceedings of the National Academy of Sciences of the United States of America - 22 Dec 1998
Semizarov D, Glesne D, Laouar A, Schiebel K, Huberman E
Abstract excerpt
To identify genes involved in macrophage development, we used the differential display technique and compared the gene expression profiles for human myeloid HL-60 leukemia cell lines susceptible and resistant to macrophage maturation. We identified a gene coding for a protein kinase, protein kinase X (PRKX), which was expressed in the maturation-susceptible, but not in the resistant, cell line. The expression of...
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