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Article

Autophagy is an important event for megakaryocytic differentiation of the chronic myelogenous leukemia K562 cell line

16 Nov 2009

Abstract excerpt

Autophagy is a highly conserved catabolic process for the elimination and recycling of organelles and macromolecules, characterized by the formation of double-membrane vesicles called autophagosomes. To date, the function of autophagy in cell differentiation is poorly documented. Here, we investigated the possibility that megakaryocytic differentiation of the Chronic Myelogenous Leukemia (CML) cell line K562, a...

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PMID: 19786835
DOI: 10.4161/auto.5.8.9889

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