Article
Roles of Rho-associated kinase in cytokinesis; mutations in Rho-associated kinase phosphorylation sites impair cytokinetic segregation of glial filaments.
The Journal of cell biology - 30 Nov 1998
Yasui Y, Amano M, Nagata K, Inagaki N, Nakamura H, Saya H, Kaibuchi K, Inagaki M
Abstract excerpt
Rho-associated kinase (Rho-kinase), which is activated by the small GTPase Rho, regulates formation of stress fibers and focal adhesions, myosin fiber organization, and neurite retraction through the phosphorylation of cytoskeletal proteins, including myosin light chain, the ERM family proteins (...
Topics
- Amino Acid Sequence
- Animals
- Catalytic Domain
- Cell Division
- Cytoskeleton
- Female
- Glial Fibrillary Acidic Protein
- Intermediate Filaments
- Intracellular Signaling Peptides and Proteins
- L Cells
- Mice