Article
Protein kinases required for segregation of vimentin filaments in mitotic process.
Oncogene - 24 May 2001
Yasui Y, Goto H, Matsui S, Manser E, Lim L, Nagata Ki, Inagaki M
Abstract excerpt
Vimentin, one of type III intermediate filament (IF) proteins, is expressed not only in mesenchymal cells but also in most types of tumor cells. In the present study, we introduced several types of vimentin mutated at putative phosphorylation sites in its amino-terminal head domain into type III IF-negative T24 cells. Site-specific mutation induced the formation of an unusually long bridge-like IF structure...
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