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Article

The novel Rho-family GTPase rif regulates coordinated actin-based membrane rearrangements.

Current biology : CB - 2 Nov 2000

Ellis S, Mellor H

Abstract excerpt

Small GTPases of the Rho family have a critical role in controlling cell morphology, motility and adhesion through dynamic regulation of the actin cytoskeleton [1,2]. Individual Rho GTPases have been shown to regulate distinct components of the cytoskeletal architecture; RhoA stimulates the bundling of actin filaments into stress fibres [3], Rac reorganises actin to produce membrane sheets or lamellipodia [4] and...

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Identifiers

PMID: 11084341
DOI: 10.1016/s0960-9822(00)00777-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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