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Article

WHIMP links the actin nucleation machinery to Src-family kinase signaling during protrusion and motility

2020-01-14

Abstract excerpt

<h4>ABSTRACT</h4> Cell motility is governed by cooperation between the Arp2/3 complex and nucleation factors from the Wiskott - Aldrich Syndrome Protein (WASP) family, which together assemble actin filament networks to drive membrane protrusion. Here we identify WHIMP (WAVE Homology In Membrane Protrusions) as a new member of the WASP family. The Whimp gene is encoded on the X-chromosome of multiple animals, in...

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Identifiers and source

Literature Corpus work
61e13f88-d314-5c57-bf68-0119a88a1c56
DOI
10.1101/2020.01.14.906784
Open publication

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WHIMP links the actin nucleation machinery to Src-family kinase signaling during protrusion and motilityDOI 10.1101/2020.01.14.906784
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