Article
Functional characterization of transcriptional regulatory elements in the upstream region and intron 1 of the human S6 ribosomal protein gene.
The Biochemical journal - 1 Dec 1998
Antoine M, Kiefer P
Abstract excerpt
Expression of housekeeping genes involves regulation at comparable levels in a wide spectrum of cells. To define the cis-regulatory elements in the human S6 ribosomal protein (rpS6) gene, we made a series of deletions of the upstream non-transcribed region, including or excluding exon 1 or intron...
Topics
- Animals
- COS Cells
- DNA-Binding Proteins
- Erythroid-Specific DNA-Binding Factors
- HeLa Cells
- Humans
- Introns
- Mutation
- Nuclear Proteins
- Promoter Regions, Genetic
- Recombinant Proteins
- Regulatory Sequences, Nucleic Acid
- Ribosomal Protein S6
- Ribosomal Proteins
- Sequence Deletion
- Transcription Factors
- Transcription, Genetic
- Transfection