Article
In vivo expression of a variant human U6 RNA from a unique, internal promoter.
Biochemistry - 15 Sept 1998
Tichelaar J W, Wieben E D, Reddy R, Vrabel A, Camacho P
Abstract excerpt
We previously isolated a variant of the human U6 small nuclear RNA gene (87U6) and demonstrated that transcription of this gene is controlled by a novel internal promoter. It has now been shown that two blocks of sequence within the coding region are both necessary and sufficient to direct expression of 87U6 in transcription assays performed in vitro. In addition, 87U6 is expressed in vivo and can assemble into...
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