In vivo expression of a variant human U6 RNA from a unique, internal promoter.

doi:10.1021/bi9811361

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Article

In vivo expression of a variant human U6 RNA from a unique, internal promoter.

Biochemistry - 15 Sept 1998

Tichelaar J W, Wieben E D, Reddy R, Vrabel A, Camacho P

Abstract excerpt

We previously isolated a variant of the human U6 small nuclear RNA gene (87U6) and demonstrated that transcription of this gene is controlled by a novel internal promoter. It has now been shown that two blocks of sequence within the coding region are both necessary and sufficient to direct expres...

Topics

Animals
Base Sequence
Cell Nucleus
Chemical Precipitation
Gene Expression Regulation
Genetic Variation
HeLa Cells
Humans
Molecular Sequence Data
Oocytes
Organophosphates
Promoter Regions, Genetic
RNA Caps
RNA, Small Nuclear
Ribonucleoproteins
Transcription, Genetic
Xenopus laevis

Source

Open in PubMed

Identifiers

PMID: 9737874
DOI: 10.1021/bi9811361

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9737874-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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