Article
Ribosomal gene promoter domains can function as artificial enhancers of RNA polymerase I transcription, supporting a promoter origin for natural enhancers in Xenopus.
Proceedings of the National Academy of Sciences of the United States of America - 18 Jan 1994
Pikaard C S
Abstract excerpt
Enhancers of RNA polymerase I transcription in higher eukaryotes are repetitive elements within the intergenic spacers of rRNA genes. In Xenopus and mouse, enhancers and the gene promoter bind the activator protein, upstream binding factor, and in Xenopus, enhancers also share sequence similarity...
Topics
- Animals
- Base Sequence
- Biological Evolution
- DNA, Ribosomal
- Enhancer Elements, Genetic
- Female
- Mice
- Molecular Sequence Data
- Mutation
- Oocytes
- Promoter Regions, Genetic
- RNA Polymerase I
- RNA, Ribosomal
- Repetitive Sequences, Nucleic Acid
- Species Specificity
- Transcription, Genetic
- Xenopus laevis