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Article

Construction of an in vivo-regulated U6 snRNA transcription unit as a tool to study U6 function.

RNA (New York, N.Y.) - 1 Feb 1998

Luukkonen B G, Séraphin B

Abstract excerpt

U6 snRNA is the only spliceosomal snRNA transcribed by RNA polymerase III in yeast. We have constructed a regulated U6 snRNA transcription unit by introducing the binding site for the Escherichia coli lacI repressor protein in the U6 snRNA promoter. GAL-induced expression of lacI protein led to a decrease in U6 snRNA levels and blocked cell growth. lacI dissociation from the promoter, and consequent U6 snRNA...

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Source

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Identifiers

PMID: 9570323
PMCID: PMC1369612

Genes

GAL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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