Equilibrium unfolding (folding) pathway of a model H-type pseudoknotted RNA: the role of magnesium ions in stability.

doi:10.1021/bi981726z

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Article

Equilibrium unfolding (folding) pathway of a model H-type pseudoknotted RNA: the role of magnesium ions in stability.

Biochemistry - 17 Nov 1998

Nixon P L, Giedroc D P

Abstract excerpt

In T2 and related T-even bacteriophages, the upstream autoregulatory mRNA leader sequence of gene 32 folds into a simple tertiary structural motif, a hairpin (H)-type pseudoknot. This pseudoknot is derived from 32 contiguous nucleotides which form two coaxially stacked helical stems that adopt a...

Topics

Base Pairing
DNA-Binding Proteins
Magnesium
Models, Molecular
Mutation
Myoviridae
Nucleic Acid Conformation
Protein Denaturation
Protein Folding
RNA, Messenger
RNA, Viral
Thermodynamics
Viral Proteins

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