Article
Non-nearest neighbor effects on the thermodynamics of unfolding of a model mRNA pseudoknot.
Journal of molecular biology - 12 Jun 1998
Theimer C A, Wang Y, Hoffman D W, Krisch H M, Giedroc D P
Abstract excerpt
The upstream autoregulatory mRNA leader sequence of gene 32 of 17 T-even and related bacteriophages folds into a simple tertiary structural motif, a hairpin-type RNA pseudoknot. In phage T4, the pseudoknot is contained within 28 contiguous nucleotides which adopt a pseudocontinuous helical structure derived from two coaxially stacked helical stems of four (stem 1) and seven (stem 2) base-pairs connected by two...
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