Article
Non-nearest neighbor effects on the thermodynamics of unfolding of a model mRNA pseudoknot.
Journal of molecular biology - 12 Jun 1998
Theimer C A, Wang Y, Hoffman D W, Krisch H M, Giedroc D P
Abstract excerpt
The upstream autoregulatory mRNA leader sequence of gene 32 of 17 T-even and related bacteriophages folds into a simple tertiary structural motif, a hairpin-type RNA pseudoknot. In phage T4, the pseudoknot is contained within 28 contiguous nucleotides which adopt a pseudocontinuous helical struct...
Topics
- Base Sequence
- Genes, Viral
- Magnesium
- Magnetic Resonance Spectroscopy
- Molecular Sequence Data
- Mutation
- Nucleic Acid Conformation
- Nucleic Acid Denaturation
- RNA, Messenger
- Ribonuclease T1
- Sequence Alignment
- T-Phages
- Temperature
- Thermodynamics