Article
Thermodynamics of folding a pseudoknotted mRNA fragment.
Journal of molecular biology - 12 Aug 1994
Gluick T C, Draper D E
Abstract excerpt
A sequence in the leader and first gene of the Escherichia coli alpha mRNA folds into a complex pseudoknot structure that is required for binding of a translational repressor. The thermal denaturation of a 112 nt RNA containing this structure has been followed by calorimetry and UV hyperchromicit...
Topics
- Base Sequence
- Binding Sites
- Calorimetry, Differential Scanning
- Hydrogen Bonding
- Magnesium
- Molecular Sequence Data
- Mutation
- Nucleic Acid Conformation
- Nucleic Acid Denaturation
- Potassium
- RNA, Bacterial
- RNA, Messenger
