Article
Characterization of the mechanical unfolding of RNA pseudoknots.
Journal of molecular biology - 11 Jan 2008
Green Lisa, Kim Chul-Hyun, Bustamante Carlos, Tinoco Ignacio
Abstract excerpt
The pseudoknot is an important RNA structural element that provides an excellent model system for studying the contributions of tertiary interactions to RNA stability and to folding kinetics. RNA pseudoknots are also of interest because of their key role in the control of ribosomal frameshifting by viral RNAs. Their mechanical properties are directly relevant to their unfolding by ribosomes during translation. We...
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