Article
Allelic loss on chromosome 9q is associated with lymph node metastasis of primary breast cancer.
Japanese journal of cancer research : Gann - 1 Sept 1998
Minobe K, Onda M, Iida A, Kasumi F, Sakamoto G, Nakamura Y, Emi M
Abstract excerpt
Frequent allelic losses on chromosome 9 are seen in a wide variety of human tumors; moreover, two genes (P16 and PTC) whose mutant alleles confer predispositions to some inherited cancer syndromes have been identified on this chromosome. Using 15 highly polymorphic microsatellite markers distribu...
Topics
- Adenocarcinoma, Scirrhous
- Alleles
- Autoradiography
- Breast Neoplasms
- Chromosome Mapping
- Chromosomes, Human, Pair 9
- Gene Deletion
- Genes, Tumor Suppressor
- Humans
- Loss of Heterozygosity
- Lymphatic Metastasis
