Article
Allelic loss on chromosome 9q is associated with lymph node metastasis of primary breast cancer.
Japanese journal of cancer research : Gann - 1 Sept 1998
Minobe K, Onda M, Iida A, Kasumi F, Sakamoto G, Nakamura Y, Emi M
Abstract excerpt
Frequent allelic losses on chromosome 9 are seen in a wide variety of human tumors; moreover, two genes (P16 and PTC) whose mutant alleles confer predispositions to some inherited cancer syndromes have been identified on this chromosome. Using 15 highly polymorphic microsatellite markers distributed on both arms of chromosome 9, we tested 96 primary breast carcinomas for allelic loss in order to define the...
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