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Article

11q23 allelic loss is associated with regional lymph node metastasis in melanoma.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Aug 2000

Herbst R A, Mommert S, Casper U, Podewski E K, Kiehl P, Kapp A, Weiss J

Abstract excerpt

Genetic alterations of the long arm of chromosome 11 have been implicated in melanoma pathogenesis, and we recently identified two distinct regions of common allelic loss in chromosomal band 11q23. To establish the point in time of melanoma tumorigenesis at which these two putative tumor suppressor loci become relevant, we investigated allelic loss [loss of heterozygosity (LOH)] in both chromosomal regions in...

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PMID: 10955807

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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