Article
Allelotype of head and neck squamous cell carcinoma.
Cancer research - 1 Mar 1994
Nawroz H, van der Riet P, Hruban R H, Koch W, Ruppert J M, Sidransky D
Abstract excerpt
To gain a better understanding of the molecular changes in head and neck squamous cell carcinoma, we tested every autosomal arm of 29 primary head and neck tumors for allelic loss. Fifty-eight microsatellite markers were used with at least two-thirds of patients informative for each chromosomal arm tested. A high frequency of allelic loss was found on chromosome 9p where 21 of 29 (72%) tumors had loss of...
Topics
- Alleles
- Carcinoma, Squamous Cell
- Chromosomes, Human, Pair 3
- Chromosomes, Human, Pair 9
- Gene Deletion
- Head and Neck Neoplasms
- Humans