Article
A region of homozygous deletion on chromosome 9p21-22 in primary nasopharyngeal carcinoma.
Cancer research - 1 Aug 1994
Huang D P, Lo K W, van Hasselt C A, Woo J K, Choi P H, Leung S F, Cheung S T, Cairns P, Sidransky D, Lee J C
Abstract excerpt
Using 21 microsatellite polymorphic markers spanning both p and q arms, we have performed detailed deletion mapping on chromosome 9 in 18 primary nasopharyngeal carcinomas. All 18 tumors were informative at multiple loci. Eleven of the 18 cases (61%) demonstrated allelic deletion of chromosome 9. Among these 11, 6 cases are likely to be tumors with monosomy of chromosome 9. The other 5 cases demonstrated partial...
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