Article

Allelic loss on chromosome 1p is Associated with progression and lymph node metastasis of primary breast carcinoma

1998-01-15

Abstract excerpt

BACKGROUND Frequent allelic losses on the short arm of chromosome 1 have been observed in a wide variety of human tumors. Cytogenetic and molecular genetic studies in breast carcinomas have shown frequent alterations on chromosome 1, involving loss of 1p or gain of 1q. METHODS To define the locations of tumor suppressor genes, 143 primary breast carcinomas were examined for allelic loss using 15 highly polymorphic...

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Literature Corpus work: c94f3ca4-b102-545d-8c68-04aada013828
DOI: 10.1002/(sici)1097-0142(19980115)82:2<323::aid-cncr11>3.0.co;2-0

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