Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Frequent allele loss on 9p21-22 defines a smallest common region in the vicinity of the CDKN2 gene in sporadic breast cancer.

Genes, chromosomes & cancer - 1 Sept 1996

An H X, Niederacher D, Picard F, van Roeyen C, Bender H G, Beckmann M W

Abstract excerpt

Genetic studies of chromosome arm 9p have indicated the presence of one or more tumor suppressor genes involved in genetic susceptibility to various types of human cancers. To define the extent of the specific deletion of 9p21-22 in human breast cancer, we have analyzed loss of heterozygosity and homozygous deletion of 9p21-22 in 68 paired blood and tumor samples by using fluorescent multiplex polymerase chain...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Carrier Proteins
Share to Chromosome Aberrations

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA, Neoplasm

Share to Gene Deletion

Share to Genetic Markers

Share to Genotype

Share to Polymerase Chain Reaction

Source

Identifiers

PMID: 8889502
DOI: 10.1002/(SICI)1098-2264(199609)17:1<14::AID-GCC3>3.0.CO;2-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Frequent allele loss on 9p21-22 defines a smallest common region in the vicinity of the CDKN2 gene in sporadic breast cancer.PMID 8889502Read ↗

Characterization of chromosome 9 in human ovarian neoplasia identifies frequent genetic imbalance on 9q and rare alterations involving 9p, including CDKN2.Semantic proximity Read ↗

Deletion mapping of chromosome region 9p21-p22 surrounding the CDKN2 locus in melanoma.Semantic proximity Read ↗

Allelic loss on chromosome 9q is associated with lymph node metastasis of primary breast cancer.Semantic proximity Read ↗

Chromosome 9p allelic loss and p16/CDKN2 in breast cancer and evidence of p16 inactivation in immortal breast epithelial cells.Semantic proximity Read ↗

Frequent loss of chromosome 9p21-22 early in head and neck cancer progression.Semantic proximity Read ↗

Loss of heterozygosity on chromosome 9 in human breast cancer: association with clinical variables and genetic changes at other chromosome regions.Semantic proximity Read ↗

High-resolution analysis of 9p loss in human cancer cells using single nucleotide polymorphism-based mapping arrays.Semantic proximity Read ↗

Genome-wide linkage scan in Dutch hereditary non-BRCA1/2 breast cancer families identifies 9q21-22 as a putative breast cancer susceptibility locus.Semantic proximity Read ↗

Homozygous deletions within human chromosome band 9p21 in melanoma.Semantic proximity Read ↗

High frequency of CDKN2A alterations in esophageal squamous cell carcinoma from a high-risk Chinese population.Semantic proximity Read ↗

A region of homozygous deletion on chromosome 9p21-22 in primary nasopharyngeal carcinoma.Semantic proximity Read ↗

Two regions of deletion in 9p22- p24 in neuroblastoma are frequently observed in favorable tumors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.