Frequent allele loss on 9p21-22 defines a smallest common region in the vicinity of the CDKN2 gene in sporadic breast cancer.

doi:10.1002/(SICI)1098-2264(199609)17:1<14::AID-GCC3>3.0.CO;2-5

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Article

Frequent allele loss on 9p21-22 defines a smallest common region in the vicinity of the CDKN2 gene in sporadic breast cancer.

Genes, chromosomes & cancer - 1 Sept 1996

An H X, Niederacher D, Picard F, van Roeyen C, Bender H G, Beckmann M W

Abstract excerpt

Genetic studies of chromosome arm 9p have indicated the presence of one or more tumor suppressor genes involved in genetic susceptibility to various types of human cancers. To define the extent of the specific deletion of 9p21-22 in human breast cancer, we have analyzed loss of heterozygosity and...

Topics

Alleles
Breast Neoplasms
Carrier Proteins
Chromosome Aberrations
Chromosomes, Human, Pair 9
Cyclin-Dependent Kinase Inhibitor p16
DNA, Neoplasm
Gene Deletion
Genes, Tumor Suppressor
Genetic Markers
Genotype
Humans
Microsatellite Repeats
Polymerase Chain Reaction

Source

Open in PubMed

Identifiers

PMID: 8889502
DOI: 10.1002/(SICI)1098-2264(199609)17:1<14::AID-GCC3>3.0.CO;2-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8889502-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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