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Genome-wide linkage scan in Dutch hereditary non-BRCA1/2 breast cancer families identifies 9q21-22 as a putative breast cancer susceptibility locus.

Genes, chromosomes & cancer - 1 Nov 2008

Oldenburg Rogier A, Kroeze-Jansema Karin H G, Houwing-Duistermaat Jeanine J, Bayley Jean-Pierre, Dambrot Cheryl, van Asperen Christi J, van den Ouweland Ans M W, Bakker Bert, van Beers Erik H, Nederlof Petra M, Vasen Hans, Hoogerbrugge Nicoline, Cornelisse Cees J, Meijers-Heijboer Hanne, Devilee Peter

Abstract excerpt

Breast cancer accounts for over 20% of all female cancers. A positive family history remains one of the most important risk factors for the disease, with first-degree relatives of patients having a twofold elevated risk. Known breast cancer susceptibility genes such as BRCA1 and BRCA2 explain only 20-25% of this risk, suggesting the existence of other breast cancer susceptibility genes. Here, we report the...

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Identifiers

PMID: 18663745
DOI: 10.1002/gcc.20597

Genes

BRCA1
BRCA2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genome-wide linkage scan in Dutch hereditary non-BRCA1/2 breast cancer families identifies 9q21-22 as a putative breast cancer susceptibility locus.PMID 18663745Read ↗

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