Article
Frequent loss of chromosome 9 in human primary non-small cell lung cancer.
Cancer research - 1 Feb 1994
Merlo A, Gabrielson E, Askin F, Sidransky D
Abstract excerpt
We analyzed the pattern of allelic loss on chromosome 9 in 40 primary human non-small cell lung cancers including 16 squamous cell, 18 adeno-, and 6 large cell carcinomas. Using 24 polymorphic microsatellite markers spanning chromosome 9, we found that 27 of 40 (67.5%) of these neoplasms displayed loss of heterozygosity (LOH) on chromosome 9. Most tumors showed LOH for all informative markers on both chromosomal...
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