Frequent loss of chromosome 9 in human primary non-small cell lung cancer.

Article

Frequent loss of chromosome 9 in human primary non-small cell lung cancer.

Cancer research - 1 Feb 1994

Merlo A, Gabrielson E, Askin F, Sidransky D

Abstract excerpt

We analyzed the pattern of allelic loss on chromosome 9 in 40 primary human non-small cell lung cancers including 16 squamous cell, 18 adeno-, and 6 large cell carcinomas. Using 24 polymorphic microsatellite markers spanning chromosome 9, we found that 27 of 40 (67.5%) of these neoplasms displaye...

Topics

Aged
Aged, 80 and over
Alleles
Carcinoma, Non-Small-Cell Lung
Chromosome Deletion
Chromosomes, Human, Pair 9
Female
Genes, Tumor Suppressor
Genetic Markers
Heterozygote
Humans
Lung Neoplasms
Male
Middle Aged
Polymorphism, Genetic

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