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Article

Loss of heterozygosity on chromosome 9 in human breast cancer: association with clinical variables and genetic changes at other chromosome regions.

International journal of cancer - 20 Dec 1995

Eiriksdottir G, Sigurdsson A, Jonasson J G, Agnarsson B A, Sigurdsson H, Gudmundsson J, Bergthorsson J T, Barkardottir R B, Egilsson V, Ingvarsson S

Abstract excerpt

Primary breast tumors were tested for loss of heterozygosity (LOH), on chromosome 9p with microsatellite markers restricted to a 28 cM region including the MTS1 gene. LOH was found with at least 1 marker in 38% of the 201 cases analyzed. A high frequency of deletions was detected at the 9p23-p21 region, indicating a tumor suppressor gene(s) important for breast cancer tumorigenesis. Tumors with and without LOH on...

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PMID: 8550238
DOI: 10.1002/ijc.2910640605

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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