Article
Two target regions of allelic loss on chromosome 9 in urinary-bladder cancer.
Japanese journal of cancer research : Gann - 1 Sept 1999
Ohgaki K, Minobe K, Kurose K, Iida A, Habuchi T, Ogawa O, Kubota Y, Akimoto M, Emi M
Abstract excerpt
Allelic losses on chromosome 9 are common in a wide variety of human tumors; moreover, two predisposing loci for some inherited cancer syndromes, i.e., familial malignant melanoma and Gorlin syndrome, have been identified on this chromosome. To define the location of putative tumor suppressor genes involved in cancer of the urinary bladder, 85 bladder cancers were examined for allelic loss at 18 microsatellite...
Topics
- Chromosome Mapping
- Chromosomes, Human, Pair 9
- Humans
- Loss of Heterozygosity
- Membrane Proteins
- Mutation
- Patched Receptors
- Patched-1 Receptor
- Polymerase Chain Reaction
- Polymorphism, Single-Stranded Conformational
- Receptors, Cell Surface
- Urinary Bladder Neoplasms