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Article

Mutations in Bartonella bacilliformis gyrB confer resistance to coumermycin A1.

Antimicrobial agents and chemotherapy - 1 Nov 1998

Battisti J M, Smitherman L S, Samuels D S, Minnick M F

Abstract excerpt

This study describes the first isolation and characterization of spontaneous mutants conferring natural resistance to an antibiotic for any Bartonella species. The Bartonella bacilliformis gyrB gene, which encodes the B subunit of DNA gyrase, was cloned and sequenced. The gyrB open reading frame...

Topics

Amino Acid Sequence
Aminocoumarins
Anti-Bacterial Agents
Bartonella
Base Sequence
Cloning, Molecular
Coumarins
DNA Gyrase
DNA Topoisomerases, Type II
Drug Resistance, Microbial
Enzyme Inhibitors
Genes, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Microbial Sensitivity Tests

Molecular Sequence Data

Mutation

Nucleic Acid Hybridization

Topoisomerase II Inhibitors

Source

Open in PubMed Open full text

Identifiers

PMID: 9797224
DOI: 10.1128/AAC.42.11.2906
PMCID: PMC105964

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9797224-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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