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Article

Mutations in Bartonella bacilliformis gyrB confer resistance to coumermycin A1.

Antimicrobial agents and chemotherapy - 1 Nov 1998

Battisti J M, Smitherman L S, Samuels D S, Minnick M F

Abstract excerpt

This study describes the first isolation and characterization of spontaneous mutants conferring natural resistance to an antibiotic for any Bartonella species. The Bartonella bacilliformis gyrB gene, which encodes the B subunit of DNA gyrase, was cloned and sequenced. The gyrB open reading frame (ORF) is 2,079 bp and encodes a deduced amino acid sequence of 692 residues, corresponding to a predicted protein of...

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Identifiers

PMID: 9797224
DOI: 10.1128/AAC.42.11.2906
PMCID: PMC105964

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Source receipt: pubmed, retrieved 7 Sept 2026.

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