Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Role of Gas1 down-regulation in mitogenic stimulation of quiescent NIH3T3 cells by v-Src.

Oncogene - 1 Oct 1998

Grossi M, La Rocca S A, Pierluigi G, Vannucchi S, Ruaro E M, Schneider C, Tatò F

Abstract excerpt

Quiescent mammalian fibroblasts can be induced to reenter the cell cycle by growth factors and oncoproteins. We studied the pathway(s) through which v-Src, the oncogenic tyrosine kinase encoded by the v-src oncogene of Rous sarcoma virus, forces serum-starved NIH3T3 cells to enter S-phase. To this purpose, we isolated and characterized a polyclonal population of NIH3T3 cells transformed by the MR31 retroviral...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3T3 Cells
Share to Cell Cycle Proteins
Share to Cell Division

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cell Transformation, Neoplastic

Share to Gene Expression

Share to Membrane Proteins

Share to Phenotype

Source

Identifiers

PMID: 9796692
DOI: 10.1038/sj.onc.1202090

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Role of Gas1 down-regulation in mitogenic stimulation of quiescent NIH3T3 cells by v-Src.PMID 9796692Read ↗

Mitogenesis by v-Src: fluctuations throughout G1 of classical immediate early AP-1 and mitogen-activated protein kinase responses that parallel the need for the oncoprotein.Semantic proximity Read ↗

Functions of the v-Src protein tyrosine kinase.Semantic proximity Read ↗

Activated Src abrogates the Myc requirement for the G0/G1 transition but not for the G1/S transition.Semantic proximity Read ↗

Mitogenesis of quiescent chick fibroblasts by v-Src: dependence on events at the membrane leading to early changes in AP-1.Semantic proximity Read ↗

Dissection of c-myc domains involved in S phase induction of NIH3T3 fibroblasts.Semantic proximity Read ↗

Mutations in v-Src SH3 and catalytic domains that jointly confer temperature-sensitive transformation with minimal temperature-dependent changes in cellular tyrosine phosphorylation.Semantic proximity Read ↗

Slow time-dependent cellular transformation induced at restrictive temperature by ts-src mutants.Semantic proximity Read ↗

Stat3 Activation Is Required for Cellular Transformation by v- <i>src</i>Semantic proximity Read ↗

The v-src oncogene may not be responsible for the increased radioresistance of hematopoietic progenitor cells expressing v-src.Semantic proximity Read ↗

Functional dissection of transformation by c‐Src and v‐SrcSemantic proximity Read ↗

Reversible transformation by v-sis: a model cell line for analysis of transformation by antisense methods.Semantic proximity Read ↗

Cytokinesis Failure Leading to Chromosome Instability in v-Src-Induced Oncogenesis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.