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Article

Cytokinesis Failure Leading to Chromosome Instability in v-Src-Induced Oncogenesis.

International journal of molecular sciences - 12 Apr 2017

Nakayama Yuji, Soeda Shuhei, Ikeuchi Masayoshi, Kakae Keiko, Yamaguchi Naoto

Abstract excerpt

v-Src, an oncogene found in Rous sarcoma virus, is a constitutively active variant of c-Src. Activation of Src is observed frequently in colorectal and breast cancers, and is critical in tumor progression through multiple processes. However, in some experimental conditions, v-Src causes growth suppression and apoptosis. In this review, we highlight recent progress in our understanding of cytokinesis failure and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28417908
DOI: 10.3390/ijms18040811
PMCID: PMC5412395

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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