Dissection of c-myc domains involved in S phase induction of NIH3T3 fibroblasts.

Article

Dissection of c-myc domains involved in S phase induction of NIH3T3 fibroblasts.

Oncogene - 1 Jun 1994

Goruppi S, Gustincich S, Brancolini C, Lee W M, Schneider C

Abstract excerpt

The product of the c-myc proto-oncogene is an important regulator of cell proliferation and apoptosis in murine fibroblasts. Addition of the tumor promoter, phorbol myristate acetate (PMA), prevents apoptotic cell death induced by low serum concentrations in NIH3T3 cells that constitutively expre...

Topics

3T3 Cells
Animals
Apoptosis
Cells, Cultured
Genes, myc
Mice
Microinjections
Mutation
Proto-Oncogene Mas
S Phase
Tetradecanoylphorbol Acetate

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