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Article

Dissection of c-myc domains involved in S phase induction of NIH3T3 fibroblasts.

Oncogene - 1 Jun 1994

Goruppi S, Gustincich S, Brancolini C, Lee W M, Schneider C

Abstract excerpt

The product of the c-myc proto-oncogene is an important regulator of cell proliferation and apoptosis in murine fibroblasts. Addition of the tumor promoter, phorbol myristate acetate (PMA), prevents apoptotic cell death induced by low serum concentrations in NIH3T3 cells that constitutively express and are transformed by v-myc. The protective effect of PMA allowed us to analyse the ability of normal c-Myc and Myc...

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PMID: 8183547

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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