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Article

cdc2 links the Drosophila cell cycle and asymmetric division machineries.

Nature - 22 Feb 2001

Tio M, Udolph G, Yang X, Chia W

Abstract excerpt

Asymmetric cell divisions can be mediated by the preferential segregation of cell-fate determinants into one of two sibling daughters. In Drosophila neural progenitors, Inscuteable, Partner of Inscuteable and Bazooka localize as an apical cortical complex at interphase, which directs the apical-basal orientation of the mitotic spindle as well as the basal/cortical localization of the cell-fate determinants Numb...

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Identifiers

PMID: 11234018
DOI: 10.1038/35059124

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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cdc2 links the Drosophila cell cycle and asymmetric division machineries.PMID 11234018Read ↗

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Role of inscuteable in orienting asymmetric cell divisions in Drosophila.Semantic proximity Read ↗

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Miranda as a multidomain adapter linking apically localized Inscuteable and basally localized Staufen and Prospero during asymmetric cell division in Drosophila.Semantic proximity Read ↗

Identification of Miranda protein domains regulating asymmetric cortical localization, cargo binding, and cortical release.Semantic proximity Read ↗

Cell division genes promote asymmetric interaction between Numb and Notch in the Drosophila CNS.Semantic proximity Read ↗

Role of cortical tumour-suppressor proteins in asymmetric division of Drosophila neuroblast.Semantic proximity Read ↗

Binary sibling neuronal cell fate decisions in the Drosophila embryonic central nervous system are nonstochastic and require inscuteable-mediated asymmetry of ganglion mother cells.Semantic proximity Read ↗

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