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Article

Bazooka recruits Inscuteable to orient asymmetric cell divisions in Drosophila neuroblasts.

Nature - 2 Dec 1999

Schober M, Schaefer M, Knoblich J A

Abstract excerpt

Asymmetric cell divisions can be generated by the segregation of determinants into one of the two daughter cells. In Drosophila, neuroblasts divide asymmetrically along the apical-basal axis shortly after their delamination from the neuroectodermal epithelium. Several proteins, including Numb and Miranda, segregate into the basal daughter cell and are needed for the determination of its correct cell fate. Both...

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Identifiers

PMID: 10591217
DOI: 10.1038/990135

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Bazooka recruits Inscuteable to orient asymmetric cell divisions in Drosophila neuroblasts.PMID 10591217Read ↗

Bazooka provides an apical cue for Inscuteable localization in Drosophila neuroblasts.Semantic proximity Read ↗

Role of inscuteable in orienting asymmetric cell divisions in Drosophila.Semantic proximity Read ↗

cdc2 links the Drosophila cell cycle and asymmetric division machineries.Semantic proximity Read ↗

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Bazooka is required for localization of determinants and controlling proliferation in the sensory organ precursor cell lineage in Drosophila.Semantic proximity Read ↗

Miranda as a multidomain adapter linking apically localized Inscuteable and basally localized Staufen and Prospero during asymmetric cell division in Drosophila.Semantic proximity Read ↗

The Partner of Inscuteable/Discs-large complex is required to establish planar polarity during asymmetric cell division in Drosophila.Semantic proximity Read ↗

Role of cortical tumour-suppressor proteins in asymmetric division of Drosophila neuroblast.Semantic proximity Read ↗

Drosophila aPKC regulates cell polarity and cell proliferation in neuroblasts and epithelia.Semantic proximity Read ↗

Apical complex genes control mitotic spindle geometry and relative size of daughter cells in Drosophila neuroblast and pI asymmetric divisions.Semantic proximity Read ↗

Miranda directs Prospero to a daughter cell during Drosophila asymmetric divisions.Semantic proximity Read ↗

A mouse homologue of Drosophila pins can asymmetrically localize and substitute for pins function in Drosophila neuroblasts.Semantic proximity Read ↗

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