Article
Rate of medial temporal lobe atrophy in typical aging and Alzheimer's disease.
Neurology - 1 Oct 1998
Jack C R, Petersen R C, Xu Y, O'Brien P C, Smith G E, Ivnik R J, Tangalos E G, Kokmen E
Abstract excerpt
OBJECTIVES: To determine the annual rates of volumetric change of the hippocampus and temporal horn in cognitively normal elderly control subjects and individually matched patients with AD, and to test the hypothesis that these rates were different. BACKGROUND: Cross-sectional studies consistentl...
Topics
- Aged
- Aged, 80 and over
- Aging
- Alzheimer Disease
- Apolipoproteins E
- Atrophy
- Comorbidity
- Diabetes Mellitus, Type 1
- Female
- Genotype
- Hippocampus
- Hormone Replacement Therapy
- Humans
- Hypertension
- Male
- Myocardial Ischemia
- Prevalence
- Reproducibility of Results