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Article

Rate of medial temporal lobe atrophy in typical aging and Alzheimer's disease.

Neurology - 1 Oct 1998

Jack C R, Petersen R C, Xu Y, O'Brien P C, Smith G E, Ivnik R J, Tangalos E G, Kokmen E

Abstract excerpt

OBJECTIVES: To determine the annual rates of volumetric change of the hippocampus and temporal horn in cognitively normal elderly control subjects and individually matched patients with AD, and to test the hypothesis that these rates were different. BACKGROUND: Cross-sectional studies consistently reveal cerebral atrophy in elderly nondemented subjects compared with healthy young adults, and greater atrophy in...

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Identifiers

PMID: 9781519
DOI: 10.1212/wnl.51.4.993
PMCID: PMC2768817

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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